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中英CLIPPERS综合征金婷

SECTION1第一部分

A73-year-oldright-handedmanwithahistoryofhypertensionandhyperlipidemiapresentedwithan18-monthhistoryofdiplopiaandunsteadygait.Healsonotedoscillatingvisionwhenturninghisheadtotheleft.Thediplopiawashorizontalandwasworselookingatobjectsonhisrightoratadistance.Overayear,hisbalanceworsenedtothepointwhereherequiredawalkerduetorecurrentfalls.Sixmonthspriortopresentation,hedevelopeddysphagia(liquidsmorethanthesolids).Hewasalsonotedtohaveshort-termmemoryproblemsinthelast3months.Onexamination,hehadmoderatecognitiveimpairmentwithaMontrealCognitiveAssessment(MoCA)scoreof20/30withpredominantdeficitsinvisuospatialfunctionsandlanguage.Glabellar,bilateralpalmomental,andsnoutreflexeswerepresent.Theleftpupilwassurgicalandnonreactivetolight,andtherewasmechanicalptosisontheleft.Hehadleftexotropiawithfulleyemovements,bilateralhorizontalgaze-evokednystagmus,andupbeatnystagmusonupgaze.Motorstrengthandtonewerenormal.Hewasdiffuselyhyperreflexicwithbilateralextensorplantarresponses.Detailedsensoryexaminationwasnormal.Dysmetriawaspresentbilaterally,moreprominentontheleft







































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